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HEAL Initiative: Understanding Individual Differences in Human Pain Conditions (R01 – Clinical Trial Optional) RFA-NS-24-021

PRF Team


17 August 2023


PRF Funding Opportunities


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The NIH HEAL Initiative is excited to announce a new notice of funding opportunity for Understanding Individual Differences in Human Pain Conditions.

This notice of funding opportunity (NOFO) from the NIH’s Helping to End Addiction Long-term® (HEAL) Initiative aims to support research aimed at holistic understanding of inter-individual or between-person differences in human pain conditions, focusing  on ‘Whole Person Health’ and enhancing pain treatment and management strategies. The goal of this NOFO is to support studies that focus on the collection of clinical and/or preclinical data to enable evidence-based modeling and understanding of inter-individual differences and/or heterogeneity of pain occurring with use of pain therapy/management, or with conditions such as a second pain condition, a comorbid health condition, a comorbid mental health condition, or conditions of use / misuse of opioids, alcohol or other substances.  

Program staff will be hosting an Applicant Webinar for those interested in learning more about RFA-NS-24-021 on Tuesday, 8/29/23 from 2:00-3:00 p.m. ET. NIH staff will provide an overview of RFA-NS-24-021 and answer general questions from prospective applicants. Registration is required.

Registration: Click here to register.

Upcoming Receipt Dates: November 7, 2023, and February 6, 2024

Questions can also be submitted prior to the event to: rachel.weinberg@nih.gov.

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